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Unusual loop-sequence flexibility of the proximal RNA replication element in EMCV.

Picornaviruses contain stable RNA structures at the 5' and 3' ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5' end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that...

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Main Authors: Jan Zoll, Marc M Hahn, Paul Gielen, Hans A Heus, Willem J G Melchers, Frank J M van Kuppeveld
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2011-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3173479?pdf=render
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