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Breaking pseudo-twofold symmetry in the poliovirus 3′-UTR Y-stem by restoring Watson–Crick base pairs

The previously described NMR structure of a 5′-CU-3′/5′-UU-3′ motif, which is highly conserved within the 3′-UTR Y-stem of poliovirus-like enteroviruses, revealed striking regularities of the local helix geometry, thus retaining the pseudo-twofold symmetry of the RNA helix. A mutant virus with both...

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Detalhes bibliográficos
Main Authors: Zoll, Jan, Tessari, Marco, Van Kuppeveld, Frank J.M., Melchers, Willem J.G., Heus, Hans A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852819/
https://ncbi.nlm.nih.gov/pubmed/17449731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.375607
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