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Unusual loop-sequence flexibility of the proximal RNA replication element in EMCV.

Picornaviruses contain stable RNA structures at the 5' and 3' ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5' end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that...

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Autori principali: Jan Zoll, Marc M Hahn, Paul Gielen, Hans A Heus, Willem J G Melchers, Frank J M van Kuppeveld
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3173479?pdf=render
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