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Unusual loop-sequence flexibility of the proximal RNA replication element in EMCV.

Picornaviruses contain stable RNA structures at the 5' and 3' ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5' end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that...

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Bibliographische Detailangaben
Hauptverfasser: Jan Zoll, Marc M Hahn, Paul Gielen, Hans A Heus, Willem J G Melchers, Frank J M van Kuppeveld
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3173479?pdf=render
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