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Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury
Abstract Background Spinal cord injury (SCI) favors a persistent pro-inflammatory macrophages/microglia-mediated response with only a transient appearance of anti-inflammatory phenotype of immune cells. However, the mechanisms controlling this special sterile inflammation after SCI are still not ful...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
BMC
2020-10-01
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श्रृंखला: | Journal of Neuroinflammation |
विषय: | |
ऑनलाइन पहुंच: | http://link.springer.com/article/10.1186/s12974-020-01973-4 |
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