Divergent Characteristics of T-Cell Receptor Repertoire Between Essential Hypertension and Aldosterone-Producing Adenoma

Aldosterone-producing adenoma (APA) is a benign adrenal tumor that results in persistent hyperaldosteronism. As one major subtype of primary aldosteronism, APA leads to secondary hypertension that is associated with immune dysregulation. However, how the adaptive immune system, particularly the T-ce...

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Main Authors: Che-Mai Chang, Kang-Yung Peng, Chieh-Kai Chan, Yu-Feng Lin, Hung-Wei Liao, Jan-Gowth Chang, Mai-Szu Wu, Vin-Cent Wu, Wei-Chiao Chang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-05-01
Serier:Frontiers in Immunology
Fag:
hypertension
aldosterone-producing adenoma (APA)
high-throughput sequencing
T-cell receptor (TCR)
TCR repertoire
Taiwan Primary Aldosteronism Investigation (TAIPAI)
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.853403/full
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