Development and validation of anti-human Alpha synuclein DNA aptamer using computer modelling techniques—an in silico study

Background: Biomarker detection strategies have, in recent years, been moving towards nucleic acid-based detection systems in the form of aptamers, short oligonucleotide sequences which have shown promise in pre-clinical and research settings. One such aptamer is M5-15, a DNA aptamer raised again...

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Main Authors: Marcus Rock, Georgios D. Zouganelis, Ana Flavia Belchior de Andrade, Samantha J. Drake, Athanasios Alexiou, Ashraf Albrakati, Gaber El-Saber Batiha, Thomas Arron Illingworth
Formáid: Artigo
Teanga:Inglês
Foilsithe: IMR Press 2022-01-01
Sraith:Journal of Integrative Neuroscience
Ábhair:
dna aptamers
in silico design
computer aided design
alpha synuclein
biomarker detection
Rochtain Ar Líne:https://article.imrpress.com/journal/JIN/21/1/10.31083/j.jin2101005/1757-448X-21-1-005.pdf
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