Multiplex Digital Quantification of β-Lactamase Genes in Antibiotic-Resistant Bacteria by Counting Gold Nanoparticle Labels on Silicon Microchips

Digital quantification based on counting of individual molecules is a promising approach for different biomedical applications due to its enhanced sensitivity. Here, we present a method for the digital detection of nucleic acids (DNA and RNA) on silicon microchips based on the counting of gold nanop...

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Main Authors: Galina V. Presnova, Denis E. Presnov, Anna A. Filippova, Ilia I. Tsiniaikin, Mariya M. Ulyashova, Maya Yu. Rubtsova
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-04-01
Serier:Biosensors
Fag:
high-sensitive digital detection
quantification
functionalized gold nanoparticles
microchips
β-lactamases
antibiotic-resistant bacteria
Online adgang:https://www.mdpi.com/2079-6374/12/4/226
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