Time since onset of disease and individual clinical markers associate with transcriptional changes in uncomplicated dengue.

BACKGROUND:Dengue virus (DENV) infection causes viral haemorrhagic fever that is characterized by extensive activation of the immune system. The aim of this study is to investigate the kinetics of the transcriptome signature changes during the course of disease and the association of genes in these...

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Huvudupphovsmän: Cornelia A M van de Weg, Henk-Jan van den Ham, Maarten A Bijl, Fatih Anfasa, Fatiha Zaaraoui-Boutahar, Beti E Dewi, Leonard Nainggolan, Wilfred F J van IJcken, Albert D M E Osterhaus, Byron E E Martina, Eric C M van Gorp, Arno C Andeweg
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2015-03-01
Serie:PLoS Neglected Tropical Diseases
Länkar:http://europepmc.org/articles/PMC4358925?pdf=render
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