Accurate ethnicity prediction from placental DNA methylation data

Abstract Background The influence of genetics on variation in DNA methylation (DNAme) is well documented. Yet confounding from population stratification is often unaccounted for in DNAme association studies. Existing approaches to address confounding by population stratification using DNAme data may...

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Detalhes bibliográficos
Main Authors: Victor Yuan, E. Magda Price, Giulia Del Gobbo, Sara Mostafavi, Brian Cox, Alexandra M. Binder, Karin B. Michels, Carmen Marsit, Wendy P. Robinson
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-08-01
Colecção:Epigenetics & Chromatin
Assuntos:
Epigenetics
DNA methylation
Microarray
Placenta
Population stratification
Machine learning
Acesso em linha:http://link.springer.com/article/10.1186/s13072-019-0296-3
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