Placental DNA Methylation Abnormalities in Prenatal Conotruncal Heart Defects

Objective: This study aims to characterize the abnormal changes in placental DNA methylation associated with conotruncal heart defects (CTDs) and the level of methylation as epigenetic biomarkers for CTDs detection.Methods: This was a prospective study involving 28 fetuses diagnosed with CTDs in the...

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Detalhes bibliográficos
Main Authors: Jingjing Liu, Yuduo Wu, Hairui Sun, Xiaowei Liu, Xiaoyan Gu, Ying Zhao, Ye Zhang, Jiancheng Han, Yihua He
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Genetics
Assuntos:
placenta
methylation
biomarkers
epigenetics
conotruncal heart defects
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2022.878063/full
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