DNA Nanocarriers for Systemic Administration: Characterization and In Vivo Bioimaging in Healthy Mice

We hereby present different DNA nanocarriers consisting of new multimodular systems (MMS), containing the cationic lipid dioleylaminesuccinylparomomycin (DNA MMS DOSP), or bis (guanidinium)-tren-cholesterol (DNA MMS BGTC), and DNA lipid nanocapsules (DNA LNCs). Active targeting of the asialoglycopro...

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Detalhes bibliográficos
Main Authors: Stephanie David, Catherine Passirani, Nathalie Carmoy, Marie Morille, Mathieu Mevel, Benoit Chatin, Jean-Pierre Benoit, Tristan Montier, Bruno Pitard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013-01-01
Colecção:Molecular Therapy: Nucleic Acids
Assuntos:
ABC phenomenon
lipid nanocapsules
multimodular systems
repeated administration
targeting
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S216225311630124X
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