Candidate Regulators of Dyslipidemia in Chromosome 1 Substitution Lines Using Liver Co-Expression Profiling Analysis

Dyslipidemia is a major risk factor for cardiovascular disease. Although many genetic factors have been unveiled, a large fraction of the phenotypic variance still needs further investigation. Chromosome 1 (Chr 1) harbors multiple gene loci that regulate blood lipid levels, and identifying functiona...

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Main Authors: Fuyi Xu, Maochun Wang, Shixian Hu, Yuxun Zhou, John Collyer, Kai Li, Hongyan Xu, Junhua Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
Colecção:Frontiers in Genetics
Assuntos:
plasma lipid
Chr 1 substitution lines
gene network
genome wide association studies
candidate gene
Acesso em linha:https://www.frontiersin.org/article/10.3389/fgene.2019.01258/full
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