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Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster

Neighboring sequences of a gene can influence its expression. In the phenomenon known as transcriptional interference, transcription at one region in the genome can repress transcription at a nearby region in cis. Transcriptional interference occurs at a number of eukaryotic loci, including the alco...

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Autori principali: Victoria Jorgensen, Jingxun Chen, Helen Vander Wende, Devon E. Harris, Alicia McCarthy, Shane Breznak, Siu Wah Wong-Deyrup, Yuzhang Chen, Prashanth Rangan, Gloria Ann Brar, Eric M. Sawyer, Leon Y. Chan, Elçin Ünal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020-05-01
Serie:G3: Genes, Genomes, Genetics
Soggetti:
transcription
interference
drosophila
adh
crispr
cas9
translation
chromatin
h3k36me3
Accesso online:http://g3journal.org/lookup/doi/10.1534/g3.119.400937
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