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Cudratricusxanthone A exhibits antitumor activity and enhances chemosensitivity to cisplatin against NSCLC via targeting EGFR

Abstract Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases and has gained considerable global attention. Epidermal growth factor receptor (EGFR) plays a key role in NSCLC treatment. NSCLC with wild-type EGFR (WT-EGFR) is not responsive to EGFR tyrosine kinase...

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Autori principali: Peiyuan Sun, Zhuoyi Wang, Ruohan Zhang, Xuanyou Li, Boxing Xu, Rui Shen, Jun Sheng, Jing Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-08-01
Serie:Scientific Reports
Soggetti:
NSCLC
EGFR
Cudratricusxanthone A
Antitumor
Chemosensitivity
Accesso online:https://doi.org/10.1038/s41598-025-14889-x
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