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Integrated genomic analysis defines molecular subgroups in dilated cardiomyopathy and identifies novel biomarkers based on machine learning methods

Aim: As the most common cardiomyopathy, dilated cardiomyopathy (DCM) often leads to progressive heart failure and sudden cardiac death. This study was designed to investigate the molecular subgroups of DCM.Methods: Three datasets of DCM were downloaded from GEO database (GSE17800, GSE79962 and GSE35...

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Principais autores: Ling-Fang Ye, Jia-Yi Weng, Li-Da Wu
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2023-02-01
סדרה:Frontiers in Genetics
נושאים:
dilated cardiomyopathy
WGCNA
molecular subgroups
lasso algorithm
SVM-RFE algorithm
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fgene.2023.1050696/full
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