Metagenomic versus targeted next-generation sequencing for detection of microorganisms in bronchoalveolar lavage fluid among renal transplantation recipients

BackgroundMetagenomic next-generation sequencing (mNGS), which provides untargeted and unbiased pathogens detection, has been extensively applied to improve diagnosis of pulmonary infection. This study aimed to compare the clinical performance between mNGS and targeted NGS (tNGS) for microbial detec...

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Главные авторы:	Zhaoru Huang, Bingxue Hu, Jinfeng Li, Min Feng, Zhigang Wang, Fengxiang Huang, Huan Xu, Lei Liu, Wenjun Shang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2024-08-01
Серии:	Frontiers in Immunology
Предметы:	kidney transplantation pulmonary infection metagenomics Next-Generation Sequencing (mNGS) targeted next-generation sequencing (tNGS) respiratory pathogens Torque teno virus
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1443057/full
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