Comparison of the diagnostic value of targeted next-generation sequencing, metagenomic next-generation sequencing, and Xpert MTB/RIF in adult pulmonary tuberculosis

Abstract Tuberculosis (TB) has high morbidity and mortality rates, and drug-resistant strains pose an increasing challenge. Traditional methods for detecting the Mycobacterium tuberculosis complex (MTBC) are insufficient for rapid clinical diagnosis. This prospective study compared the diagnostic ef...

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Bibliographic Details

Main Authors:	Qiaoqian Chen, Qionghui Yin, Jin Chen, Lijun Jin, Wenhu Guo, Mingxiang Huang
Format:	Artigo
Language:	Inglês
Published:	BMC 2026-01-01
Series:	BMC Infectious Diseases
Subjects:	Metagenomic next-generation sequencing (mNGS) Targeted next-generation sequencing (tNGS) Xpert MTB/RIF Pulmonary tuberculosis
Online Access:	https://doi.org/10.1186/s12879-026-12673-4
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