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Comparison of the diagnostic value of targeted next-generation sequencing, metagenomic next-generation sequencing, and Xpert MTB/RIF in adult pulmonary tuberculosis

Abstract Tuberculosis (TB) has high morbidity and mortality rates, and drug-resistant strains pose an increasing challenge. Traditional methods for detecting the Mycobacterium tuberculosis complex (MTBC) are insufficient for rapid clinical diagnosis. This prospective study compared the diagnostic ef...

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Principais autores: Qiaoqian Chen, Qionghui Yin, Jin Chen, Lijun Jin, Wenhu Guo, Mingxiang Huang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:BMC Infectious Diseases
Fag:
Metagenomic next-generation sequencing (mNGS)
Targeted next-generation sequencing (tNGS)
Xpert MTB/RIF
Pulmonary tuberculosis
Online adgang:https://doi.org/10.1186/s12879-026-12673-4
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