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Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes

Obesity plays an important role in the development of insulin resistance and diabetes, but the molecular mechanism that links obesity and diabetes is still not completely understood. Here, we used 146 targeted metabolomic profiles from the German KORA FF4 cohort consisting of 1715 participants and a...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Qiuling Dong, Sidra Sidra, Christian Gieger, Rui Wang-Sattler, Wolfgang Rathmann, Cornelia Prehn, Jerzy Adamski, Wolfgang Koenig, Annette Peters, Harald Grallert, Sapna Sharma
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-02-01
Schriftenreihe:Metabolites
Schlagworte:
obesity
type 2 diabetes
metabolomics
mediation
mendelian randomization
type 2 diabetes pathology
Online-Zugang:https://www.mdpi.com/2218-1989/13/2/227
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