mtDNA release promotes cGAS-STING activation and accelerated aging of postmitotic muscle cells
Abstract The mechanism regulating cellular senescence of postmitotic muscle cells is still unknown. cGAS-STING innate immune signaling was found to mediate cellular senescence in various types of cells, including postmitotic neuron cells, which however has not been explored in postmitotic muscle cel...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2024-07-01
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| Seri Bilgileri: | Cell Death and Disease |
| Online Erişim: | https://doi.org/10.1038/s41419-024-06863-8 |
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