Emergence of transferable tigecycline and eravacycline resistance gene tet(X4) in Escherichia coli isolates from Iran

Abstract Tigecycline (TGC) and eravacycline (ERV) are critical last-resort antibiotics used to treat complicated infections caused by extensively drug-resistant Gram-negative bacteria particularly carbapenem- and colistin-resistant Enterobacterales. The recent emergence of plasmid-mediated TGC resis...

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Principais autores:	Mehri Haeili, Mahdi Aghajanzadeh, Kiarash Moghaddasi, Maryam Omrani, Arash Ghodousi, Daniela Maria Cirillo
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-05-01
Series:	Scientific Reports
Assuntos:	Tigecycline resistance tet(X4) Escherichia coli Plasmid Fecal samples
Acceso en liña:	https://doi.org/10.1038/s41598-025-98206-6
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