Immaturity-Dependent Hippocampal Neurogenic Promotion and Fate Shift by Low-Dose Propofol in Neonatal Mice Revealed Through Single-Nuclei RNA-Sequencing

<b>Background:</b> Hippocampal neurogenesis in the dentate gyrus persists into adulthood and plays a crucial role in learning and memory. Early-life exposure to low-dose propofol has been reported to enhance neural development in rodent models, but detailed mechanisms remain unclear. To address this...

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Detaylı Bibliyografya

Asıl Yazarlar:	Wen Zhang, Liangtian Lan, Xuanxian Xu, Keyu Chen, Xiaoyu Yang, Xia Feng, Dihan Lu
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2025-11-01
Seri Bilgileri:	Biomedicines
Konular:	propofol hippocampal neurogenesis single-nucleus RNA-seq neural intermediate progenitor cells immature pyramidal neurons granule maturation
Online Erişim:	https://www.mdpi.com/2227-9059/13/11/2806
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