Immaturity-Dependent Hippocampal Neurogenic Promotion and Fate Shift by Low-Dose Propofol in Neonatal Mice Revealed Through Single-Nuclei RNA-Sequencing

<b>Background:</b> Hippocampal neurogenesis in the dentate gyrus persists into adulthood and plays a crucial role in learning and memory. Early-life exposure to low-dose propofol has been reported to enhance neural development in rodent models, but detailed mechanisms remain unclear. To address this...

Descrición completa

Detalles Bibliográficos

Principais autores:	Wen Zhang, Liangtian Lan, Xuanxian Xu, Keyu Chen, Xiaoyu Yang, Xia Feng, Dihan Lu
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-11-01
Series:	Biomedicines
Assuntos:	propofol hippocampal neurogenesis single-nucleus RNA-seq neural intermediate progenitor cells immature pyramidal neurons granule maturation
Acceso en liña:	https://www.mdpi.com/2227-9059/13/11/2806
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!