LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC

Abstract Background Dysregulation of transcription and cytokine expression has been implicated in the pathogenesis of a variety inflammatory diseases. The resulting imbalance between inflammatory and resolving transcriptional programs can cause an overabundance of pro-inflammatory, classically activ...

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Autori principali:	Gregory Thomas, Elizabeth Frederick, Lisa Thompson, Raphael Bar-Or, Yetti Mulugeta, Melissa Hausburg, Michael Roshon, Charles Mains, David Bar-Or
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-11-01
Serie:	Journal of Translational Medicine
Soggetti:	LMWF5A PPARγ AhR NF-κb STAT Transcription
Accesso online:	https://doi.org/10.1186/s12967-020-02626-z
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