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LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC

Abstract Background Dysregulation of transcription and cytokine expression has been implicated in the pathogenesis of a variety inflammatory diseases. The resulting imbalance between inflammatory and resolving transcriptional programs can cause an overabundance of pro-inflammatory, classically activ...

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Huvudupphov: Gregory Thomas, Elizabeth Frederick, Lisa Thompson, Raphael Bar-Or, Yetti Mulugeta, Melissa Hausburg, Michael Roshon, Charles Mains, David Bar-Or
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2020-11-01
Serie:Journal of Translational Medicine
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Länkar:https://doi.org/10.1186/s12967-020-02626-z
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