Comparative Analysis of Next-Generation Sequencing and Immunohistochemistry in MSI/MMR Testing

Objective: Loss of mismatch repair (MMR) protein expression, assessed via immunohistochemistry (IHC), and microsatellite instability (MSI) status, determined through molecular methods, are two tumor-agnostic predictive biomarkers for immunotherapy eligibility. However, there remains no consensus on...

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Detalhes bibliográficos

Principais autores:	Cisel AYDIN MERICOZ, Zeynep Secil SATILMIS, Fatma ESREFI, Gulsum CAYLAK, Burcu SAKA, Ayse ARMUTLU, Orhun Cig TASKIN, Ibrahim KULAC
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Federation of Turkish Pathology Societies 2025-09-01
coleção:	Türk Patoloji Dergisi
Assuntos:	next-generation sequencing microsatellite instability microsatellite stable mismatch repair
Acesso em linha:	https://turkjpath.org/pdf.php?id=2100
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