Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

The gene regulatory networks that coordinate the development of the cardiac and pulmonary systems are essential for terrestrial life but poorly understood. The T-box transcription factor Tbx5 is critical for both pulmonary specification and heart development, but how these activities are mechanistic...

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Detalhes bibliográficos

Principais autores:	Scott A Rankin, Jeffrey D Steimle, Xinan H Yang, Ariel B Rydeen, Kunal Agarwal, Praneet Chaturvedi, Kohta Ikegami, Michael J Herriges, Ivan P Moskowitz, Aaron M Zorn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2021-10-01
coleção:	eLife
Assuntos:	Xenopus retinoic acid cardiopulmonary lung development Tbx5 transcription factor mouse
Acesso em linha:	https://elifesciences.org/articles/69288
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