Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS

Abstract Background Neural stem cell (NSC) transplantation holds promising therapeutic potential for neurodegenerative disorders like amyotrophic lateral sclerosis (ALS). However, pre-clinical studies and early-phase clinical trials have faced challenges hindering the effective clinical translation...

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主要な著者:	Ivan Lombardi, Clelia Ferrero, Edvige Vulcano, Daniela Maria Rasà, Maurizio Gelati, Diego Pastor, Rose Mary Carletti, Silvia de la Morena, Daniela Celeste Profico, Sabrina Longobardi, Elisa Lazzarino, Elisa Perciballi, Jessica Diana Rosati, Salvador Martinez, Alessandro Vercelli, Angelo Luigi Vescovi, Marina Boido, Daniela Ferrari
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-05-01
シリーズ:	Journal of Translational Medicine
主題:	Cell therapy Neural stem cells Transplantation ALS Intracerebroventricular SOD1 model
オンライン･アクセス:	https://doi.org/10.1186/s12967-025-06529-9
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