Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS

Abstract Background Neural stem cell (NSC) transplantation holds promising therapeutic potential for neurodegenerative disorders like amyotrophic lateral sclerosis (ALS). However, pre-clinical studies and early-phase clinical trials have faced challenges hindering the effective clinical translation...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Ivan Lombardi, Clelia Ferrero, Edvige Vulcano, Daniela Maria Rasà, Maurizio Gelati, Diego Pastor, Rose Mary Carletti, Silvia de la Morena, Daniela Celeste Profico, Sabrina Longobardi, Elisa Lazzarino, Elisa Perciballi, Jessica Diana Rosati, Salvador Martinez, Alessandro Vercelli, Angelo Luigi Vescovi, Marina Boido, Daniela Ferrari
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	Journal of Translational Medicine
Témata:	Cell therapy Neural stem cells Transplantation ALS Intracerebroventricular SOD1 model
On-line přístup:	https://doi.org/10.1186/s12967-025-06529-9
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!