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Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA

Abstract Uptake of nucleobases and ascorbate is an essential process in all living organisms mediated by SLC23 transport proteins. These transmembrane carriers operate via the elevator alternating-access mechanism, and are composed of two rigid domains whose relative motion drives transport. The lac...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Benedikt T. Kuhn, Jonathan Zöller, Iwan Zimmermann, Tim Gemeinhardt, Dogukan H. Özkul, Julian D. Langer, Markus A. Seeger, Eric R. Geertsma
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2024-08-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-024-51814-8
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