Endosome and Lysosome Membrane Properties Functionally Link to γ-Secretase in Live/Intact Cells
Our unique multiplexed imaging assays employing FRET biosensors have previously detected that γ-secretase processes APP C99 primarily in late endosomes and lysosomes in live/intact neurons. Moreover we have shown that Aβ peptides are enriched in the same subcellular loci. Given that γ-secretase is i...
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| Автори: | , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2023-02-01
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| Серія: | Sensors |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/1424-8220/23/5/2651 |
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