Lowered GnT-I Activity Decreases Complex-Type N-Glycan Amounts and Results in an Aberrant Primary Motor Neuron Structure in the Spinal Cord

The attachment of sugar to proteins and lipids is a basic modification needed for organismal survival, and perturbations in glycosylation cause severe developmental and neurological difficulties. Here, we investigated the neurological consequences of N-glycan populations in the spinal cord of Wt AB...

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Principais autores:	Cody J. Hatchett, M. Kristen Hall, Abel R. Messer, Ruth A. Schwalbe
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2024-08-01
叢編:	Journal of Developmental Biology
主題:	N-glycans motor neurons oligomannose spinal cord glycomics N-acetylglucosaminyltransferase-I (GnT-I)
在線閱讀:	https://www.mdpi.com/2221-3759/12/3/21
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