Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.
Epithelial ovarian cancer (EOC) is thought to arise in part from the ovarian surface epithelium (OSE); however, the molecular events underlying this transformation are poorly understood. Germline mutations in the BRCA1 tumor suppressor gene result in a significantly increased risk of developing EOC...
保存先:
| 主要な著者: | , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2009-12-01
|
| シリーズ: | PLoS ONE |
| オンライン･アクセス: | http://europepmc.org/articles/PMC2795167?pdf=render |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|