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EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression

Dozens of histone methyltransferases have been identified and biochemically characterized, but the pathological roles of their dysfunction in human diseases such as cancer remain largely unclear. Here, we demonstrate the involvement of EHMT1, a histone lysine methyltransferase, in lung cancer. Immun...

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Autors principals: Jinkwon Lee, Kwangho Kim, Tae Young Ryu, Cho‐Rok Jung, Moo‐Seung Lee, Jung Hwa Lim, Kunhyang Park, Dae‐Soo Kim, Mi‐Young Son, Ryuji Hamamoto, Hyun‐Soo Cho
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2021-11-01
Col·lecció:Molecular Oncology
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Accés en línia:https://doi.org/10.1002/1878-0261.13050
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