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EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression

Dozens of histone methyltransferases have been identified and biochemically characterized, but the pathological roles of their dysfunction in human diseases such as cancer remain largely unclear. Here, we demonstrate the involvement of EHMT1, a histone lysine methyltransferase, in lung cancer. Immun...

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Detalles Bibliográficos
Principais autores: Jinkwon Lee, Kwangho Kim, Tae Young Ryu, Cho‐Rok Jung, Moo‐Seung Lee, Jung Hwa Lim, Kunhyang Park, Dae‐Soo Kim, Mi‐Young Son, Ryuji Hamamoto, Hyun‐Soo Cho
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2021-11-01
Series:Molecular Oncology
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Acceso en liña:https://doi.org/10.1002/1878-0261.13050
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