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Molecular Epidemiological Survey for Degenerative Myelopathy in German Shepherd Dogs in Japan: Allele Frequency and Clinical Progression Rate

Canine degenerative myelopathy (DM) is an adult-onset, chronic, progressive neurodegenerative disease reported in multiple canine breeds, including the German Shepherd Dog (GSD). Clinical signs include progressive motor neuron paralysis, which begins in the pelvic limbs and eventually leads to respi...

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Principais autores: Shinichiro Maki, Md Shafiqul Islam, Tomohito Itoh, Masanobu Nurimoto, Akira Yabuki, Yu Furusawa, Hiroaki Kamishina, Yui Kobatake, Tofazzal Md Rakib, Martia Rani Tacharina, Osamu Yamato
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Animals
Fag:
canine <i>SOD1</i> gene
degenerative myelopathy
dog breeding
German Shepherd Dog
mutant allele frequency
disease prevention
Online adgang:https://www.mdpi.com/2076-2615/12/13/1647
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