Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy
Abstract Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules. The natural compound nordihydroguaiaretic acid (NDGA) robustly increases lifespan in...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2019-10-01
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| Serier: | npj Aging and Mechanisms of Disease |
| Online adgang: | https://doi.org/10.1038/s41514-019-0037-7 |
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