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The Impact of ExoS on <italic toggle="yes">Pseudomonas aeruginosa</italic> Internalization by Epithelial Cells Is Independent of <italic toggle="yes">fleQ</italic> and Correlates with Bistability of Type Three Secretion System Gene Expression

ABSTRACT Pseudomonas aeruginosa is internalized into multiple types of epithelial cell in vitro and in vivo and yet is often regarded as an exclusively extracellular pathogen. Paradoxically, ExoS, a type three secretion system (T3SS) effector, has antiphagocytic activities but is required for intrac...

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Principais autores: Abby R. Kroken, Camille K. Chen, David J. Evans, Timothy L. Yahr, Suzanne M. J. Fleiszig
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018-07-01
Serier:mBio
Fag:
bistability
ExoS
FleQ
Pseudomonas aeruginosa
epithelial cells
host cell invasion
Online adgang:https://journals.asm.org/doi/10.1128/mBio.00668-18
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