The Impact of ExoS on <italic toggle="yes">Pseudomonas aeruginosa</italic> Internalization by Epithelial Cells Is Independent of <italic toggle="yes">fleQ</italic> and Correlates with Bistability of Type Three Secretion System Gene Expression

ABSTRACT Pseudomonas aeruginosa is internalized into multiple types of epithelial cell in vitro and in vivo and yet is often regarded as an exclusively extracellular pathogen. Paradoxically, ExoS, a type three secretion system (T3SS) effector, has antiphagocytic activities but is required for intrac...

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Autori principali:	Abby R. Kroken, Camille K. Chen, David J. Evans, Timothy L. Yahr, Suzanne M. J. Fleiszig
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2018-07-01
Serie:	mBio
Soggetti:	bistability ExoS FleQ Pseudomonas aeruginosa epithelial cells host cell invasion
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.00668-18
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