High Serine-arginine Protein Kinase 1 Expression with PTEN Loss Defines Aggressive Phenotype of Prostate Cancer Associated with Lethal Outcome and Decreased Overall Survival

Background: Serine-arginine protein kinase 1 (SRPK1) has been implicated in prostate cancer (PCa) progression. However, its prognostic value and association with ERG and PTEN expression, two of the most common genetic alterations, have not been explored fully. Objective: We assessed the prognostic v...

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Hauptverfasser:	Hatem Abou-Ouf, Hisham Assem, Sunita Ghosh, R. Jeffrey Karnes, Konstantin Stoletov, Nallasivam Palanisamy, John D. Lewis, Tarek A. Bismar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-01-01
Schriftenreihe:	European Urology Open Science
Schlagworte:	SRPK1 PTEN ERG Protein expression Immunohistochemistry Gleason score
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666168320363680
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