ALDH2 rs671 Variant Lowers Blood Pressure Via the Endothelial HSPA5–PIEZO1–eNOS Pathway

Background The inactivating ALDH2 rs671 polymorphism, present in ≈8% of the global population and up to 30% to 50% of East Asian individuals, has been negatively associated with hypertension. However, the direct role of ALDH2 (aldehyde dehydrogenase 2) dysfunction in this association, as well as the...

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Prif Awduron:	Huaqing Ye, Hongwei Yue, Shujian Wei, Kaiyi Wang, Kehui Yang, Han Du, Wentao Sang, Jialin Guo, Jingwen Wang, Yunyun Guo, Cheng Zhang, Sumei Cui, Feng Xu, Yuguo Chen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wiley 2026-01-01
Cyfres:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Pynciau:	ALDH2 ALDH2 rs671 blood pressure HSPA5 PIEZO1
Mynediad Ar-lein:	https://www.ahajournals.org/doi/10.1161/JAHA.124.040121
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!