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Establishment of a coculture system with osteochondral and synovial explants as an ex vivo inflammatory osteoarthritis model

Osteoarthritis (OA) is a whole-joint disorder involving inflammation in cartilage, synovium, and subchondral bone. An ex vivo inflammatory OA model incorporating various intra-articular tissues could facilitate the development of new OA therapeutics targeting whole joint tissue. In this study, an in...

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Principais autores: K Li, Y Zhu, M Alini, MJ Stoddart, S Grad, Z Li
Format: Artigo
Sprog:Inglês
Udgivet: Forum Multimedia Publishing LLC 2024-02-01
Serier:European Cells & Materials
Fag:
coculture
inflammation
osteoarthritis model
osteochondral explant
synovium
Online adgang:https://www.ecmjournal.org/papers/vol047/vol047a02.php
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