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Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants

Abstract Objective To explore IL11 co-expression profiles in our previously reported RNA-sequencing dataset of OA articular cartilage, in interaction with IL6, and to investigate the effects of hrIL11 administration as potential therapeutic strategy for OA articular cartilage using our biomimetic ag...

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Autors principals: Margo Tuerlings, Evelyn Houtman, Elisa J.H. Muusers, Janneke Simon, Maurice W. de Haan, Ilja Boone, Yolande F.M. Ramos, Rachid Mahdad, Ingrid Meulenbelt
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-01-01
Col·lecció:Arthritis Research & Therapy
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Accés en línia:https://doi.org/10.1186/s13075-025-03480-4
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