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Phylo-Plex: a phylogenetically informed, low-cost amplicon sequencing platform for deployable high-resolution genomic epidemiology

Abstract Genomic pathogen surveillance is a powerful tool for public health and research, but is costly and unachievable in low-resource settings. Most sub-genomic typing methods sacrifice resolution whilst remaining costly. We developed “Phylo-Plex”, a novel approach that identifies information-ric...

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Hlavní autoři: Mathew A. Beale, Vignesh Shetty, Kirsty E. Ambridge, George Lacey, Sam Dougan, William Roberts-Sengier, Beth Sampher, Florent Lassalle, Matthew J. Dorman, Mahlape P. Mahlangu, Johanna M. E. Venter, Bianca Da Costa Dias, Martha Chipinduro, Tendai M. Washaya, Luanne Rodgers, Beauty Makamure, Ethel Dauya, Michael Marks, Etienne E. Müller, Rashida A. Ferrand, Nicholas R. Thomson
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-07-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-026-75002-y
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