Prognosis and risk factors for pathological non-response to neoadjuvant chemoimmunotherapy in locally advanced esophageal squamous cell carcinoma

BackgroundNeoadjuvant chemotherapy combined with immunotherapy (NACI) is promising for treating locally advanced esophageal squamous cell carcinoma (LA-ESCC), yet a subset of patients exhibit a pathological non-response (pNR). The prognosis and risk factors for pNR to NACI remain unclear.MethodsWe r...

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Autors principals:	Jun-Peng Lin, Hui Lin, Hao He, Feng-Nian Zhuang, Wei-Jie Chen, Yu-Jie Chen, Peiyuan Wang, Hang Zhou, Wen-Wei Wei, Peng-Qiang Gao, Shuo-Yan Liu, Feng Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	esophageal squamous cell carcinoma neoadjuvant immunotherapy pathological non-response prognosis risk factors
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1815244/full
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