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Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT

The permeability transition (PT) is an increased permeation of the inner mitochondrial membrane due to the opening of the PT pore (PTP), a Ca<sup>2+</sup>-activated high conductance channel involved in Ca<sup>2+</sup> homeostasis and cell death. Alterations of the PTP have been associated with many...

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Bibliografische Detailangaben
Hauptverfasser: Andrea Carrer, Claudio Laquatra, Ludovica Tommasin, Michela Carraro
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-10-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/26/21/6463
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