Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca²⁺-Dependent Mitochondrial Permeability Transition Pore

<b>Background</b>: Tariquidar (Tq) is an inhibitor of the multidrug resistance (MDR) proteins relevant to ATP-binding cassette transporters (ABC transporters), which suppresses the ATP-dependent efflux of a variety of hydrophilic and amphipathic compounds, including anticancer drugs. Tq is a represe...

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Autores principales:	Tatiana A. Fedotcheva, Alexey G. Kruglov, Nadezhda I. Fedotcheva
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2025-06-01
Colección:	Pharmaceuticals
Materias:	tariquidar multidrug resistance mitochondria mitochondrial permeability transition pore adenine nucleotide translocase
Acceso en línea:	https://www.mdpi.com/1424-8247/18/6/924
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