Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers
Alpha-synuclein (α-syn), a major component of Lewy bodies found in Parkinson’s disease (PD) patients, has been found exported outside of cells and may mediate its toxicity via cell-to-cell transmission. Here, we reconstituted soluble, monomeric α-syn secretion by the expression of DnaJ homolog subfa...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications Ltd
2023-01-01
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| Seria: | eLife |
| Hasła przedmiotowe: | |
| Dostęp online: | https://elifesciences.org/articles/85837 |
| Etykiety: |
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