The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction
Pyroptosis is an inflammatory form of cell death involving caspase-1 or caspase-4/5/11, initiated by inflammasomes or cytoplasmic endotoxins as part of the immune defense. It is specifically characterized by Gasdermin-mediated pore formation leading to cell lysis, pyroptosis also entails the release...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2025-05-01
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| Collection: | Frontiers in Pharmacology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1586364/full |
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